The data exploitation system described within is being designed to take advantage of the existence of terabytes (or more) of data sets that have been sent down from various Air Force satellites that can be used to detect previously unknown anomalies that occurred while the satellites were operational. This wealth of information can then be used and exploited to build more reliable and robust future generations of satellites. And, because various types of data sets are sent to the ground consisting of satellite state-of-health, satellite system telemetry, as well as on-board experiments, threats to these satellites will also be able to be detected, given that the satellites have the appropriate sensors. Designing a data exploitation capability is an important development area for realizing anomaly and threat detection objectives. This paper discusses a framework to meet those objectives and is being designed for integration within the Air Force Research Laboratory modeling and simulation environment.